Zeta

Nicomp 380/ZLS
Laboratory Instruments

380/ZLS Zeta Potential and Submicron Particle Size Analyzer

The standard NICOMP 380/ZLS comes equipped with a 15 mW laser diode and PMT detector with two optical fibers: one set at 90 degrees for particle sizing and the other set at 19 degrees for zeta potential. Sample is introduced with plastic cuvettes. The standard electrodes are made of platinum. Gold is available upon request. The 380/ZLS is the only dynamic light scattering instrument designed using a modular approach. Its capabilities can be enhanced by adding one or more modules.

380/ZLS Zeta Potential Analyzer

The standard NICOMP 380/ZLS comes equipped with a 15 mW laser diode and PMT detector with one optical fiber set at 19 degrees for zeta potential analysis. Sample is introduced with plastic cuvettes. The standard electrodes are made of platinum. Gold is available upon request. Its capabilities can be enhanced by adding one or more modules.

Modules include:

AutoTitrator

This module gives the Nicomp 380/ZLS the ability to automatically make multiple measurements on the same sample over a series of different pH's or ionic concentrations. This allows iso-electric points to be determined.

Phase Analysis Light Scattering (PALS)

The use of Phase Analysis (instead of the standard amplitude analysis) allows for the more accurate and precise measurement of small Doppler shifts. This means that zeta potential measurements can be made in high ionic strength or high dielectric environments (like alcohols and organic solvents).

Autodilution

This patented feature eliminates the need for manual dilution of concentrated samples. Autodilution makes particle size analysis quick and easy, with no training required. Results are highly reproducible, especially useful for multiple users.

High Powered Lasers/APD Detector

The Nicomp 380 can be equipped with various high-powered lasers as well as a high-gain Avalanche Photodiode Detector to increase signal-to-noise and sensitivity in systems that do not scatter light well. Proteins, micelles, other macromolecular-based systems, and nanoparticles are often dilute (1 mg/ml or less) and are made of atoms that do not scatter light well. The high-powered laser options offer the ability to obtain accurate results in a short period of time.

Multiangle

Particles larger than 200 nm do not scatter light isotropically in all directions. It is possible to make DLS measurements more sensitive to certain sized particles by changing the angle of detection. The Nicomp 380 can be equipped with a mini-goniometer that moves the optical fiber between 12 and 150 degrees by 1-degree increments.

Autosampler

Offers the ability to run samples in batches unattended. Adding the 27-sample Autosampler module can increase the efficiency of data production and allows users to get more out of the Nicomp.


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